Need to scale Drupal on EC2? Check out Chapter Three's Mercury project

Josh Koenig from Chapter Three has made pre-release EC2 AMIs (pre-packaged virtual machine images) for Mercury, a project to combine Four Kitchens’ Drupal-derived, high-performance Pressflow with Varnish, Cache Router, and memcached. Initial results show it easily saturating the EC2’s pipe. Mercury instances directly update their Pressflow releases from the Four Kitchens Bazaar server.

Mercury is an exciting project for anyone who needs to run a high-traffic, Drupal-based site without having to configure a bunch of caching systems.